{"id":817,"date":"2026-09-13T09:33:10","date_gmt":"2026-09-13T01:33:10","guid":{"rendered":"https:\/\/word.hellsmart.top\/?p=817"},"modified":"2026-09-13T09:33:10","modified_gmt":"2026-09-13T01:33:10","slug":"%e3%80%90%e9%98%bf%e5%b0%94%e8%8c%a8%e6%b5%b7%e9%bb%98%e7%97%87%e6%97%a9%e6%8a%a5%e3%80%912026%e5%b9%b49%e6%9c%8813%e6%97%a5%ef%bc%9a%e6%9c%80%e6%96%b0%e7%a0%94%e7%a9%b6%e8%bf%9b%e5%b1%95%e4%b8%8e","status":"publish","type":"post","link":"https:\/\/word.hellsmart.top\/index.php\/2026\/09\/13\/%e3%80%90%e9%98%bf%e5%b0%94%e8%8c%a8%e6%b5%b7%e9%bb%98%e7%97%87%e6%97%a9%e6%8a%a5%e3%80%912026%e5%b9%b49%e6%9c%8813%e6%97%a5%ef%bc%9a%e6%9c%80%e6%96%b0%e7%a0%94%e7%a9%b6%e8%bf%9b%e5%b1%95%e4%b8%8e\/","title":{"rendered":"\u3010\u963f\u5c14\u8328\u6d77\u9ed8\u75c7\u65e9\u62a5\u30112026\u5e749\u670813\u65e5\uff1a\u6700\u65b0\u7814\u7a76\u8fdb\u5c55\u4e0e\u6cbb\u7597\u5e0c\u671b"},"content":{"rendered":"

\u65e5\u671f\uff1a<\/strong>2026\u5e749\u670813\u65e5<\/p>\n

\u4e00\u3001\u672c\u5468\u91cd\u78c5\u7814\u7a76\u4eae\u70b9<\/h2>\n

1. \u84dd\u6591\u6838\u5206\u5b50\u56fe\u8c31\u63ed\u793aAPOE\u4e0e\u963f\u5c14\u8328\u6d77\u9ed8\u75c7\u7684\u6df1\u5c42\u5173\u8054<\/h3>\n

\u53d1\u8868\u5728\u300aActa Neuropathologica\u300b\u7684\u6700\u65b0\u7814\u7a76\uff0c\u5229\u7528\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u5b66\u6280\u672f\u7ed8\u5236\u4e86\u4eba\u7c7b\u84dd\u6591\u6838\uff08Locus Coeruleus\uff09\u7684\u5206\u5b50\u56fe\u8c31\u3002\u7814\u7a76\u53d1\u73b0\uff0cAPOE\u57fa\u56e0\u53d8\u5f02\u4e0e\u795e\u7ecf\u9ed1\u8272\u7d20\uff08neuromelanin\uff09\u7684\u805a\u96c6\u76f4\u63a5\u5173\u8054\uff0c\u662f\u963f\u5c14\u8328\u6d77\u9ed8\u75c7\u65e9\u671f\u8106\u5f31\u6027\u7684\u5173\u952e\u56e0\u7d20\u3002\u84dd\u6591\u6838\u662f\u5927\u8111\u4e2d\u53bb\u7532\u80be\u4e0a\u817a\u7d20\u7684\u4e3b\u8981\u6765\u6e90\uff0c\u8d1f\u8d23\u8c03\u63a7\u7761\u7720\u3001\u89c9\u9192\u548c\u8ba4\u77e5\u529f\u80fd\uff0c\u5176\u9000\u5316\u53ef\u65e9\u4e8e\u4e34\u5e8a\u75c7\u72b6\u591a\u5e74\u51fa\u73b0\u3002\u8fd9\u9879\u53d1\u73b0\u4e3a\u65e9\u671f\u8bca\u65ad\u751f\u7269\u6807\u5fd7\u7269\u5f00\u53d1\u63d0\u4f9b\u4e86\u5168\u65b0\u9776\u70b9\u3002<\/p>\n

2. \u65b0\u578b\u82ef\u4e19\u6c28\u9178\u884d\u751f\u7269\uff1a\u963b\u6b62\u03b2-\u6dc0\u7c89\u6837\u86cb\u767d\u805a\u96c6<\/h3>\n

\u300aCurrent Alzheimer Research\u300b\u62a5\u9053\u4e86\u4e00\u9879\u836f\u7269\u5316\u5b66\u7a81\u7834\uff1a\u57fa\u4e8e\u82ef\u4e19\u6c28\u9178\u7ed3\u6784\u8bbe\u8ba1\u7684\u65b0\u578b\u5316\u5408\u7269\uff0c\u80fd\u591f\u6709\u6548\u6291\u5236A\u03b2\u86cb\u767d\u7684\u5f02\u5e38\u805a\u96c6\uff0c\u5e76\u51cf\u8f7b\u5176\u8bf1\u5bfc\u7684\u795e\u7ecf\u6bd2\u6027\u3002\u7814\u7a76\u56e2\u961f\u901a\u8fc7\u5206\u5b50\u8bbe\u8ba1\u548c\u5b9e\u9a8c\u9a8c\u8bc1\uff0c\u7b5b\u9009\u51fa\u4e86\u5177\u6709\u9ad8\u6d3b\u6027\u7684\u5019\u9009\u5206\u5b50\u3002\u8fd9\u662f”\u4ece\u7ed3\u6784\u5230\u529f\u80fd”\u7684\u836f\u7269\u8bbe\u8ba1\u601d\u8def\u5728\u963f\u5c14\u8328\u6d77\u9ed8\u75c7\u9886\u57df\u7684\u53c8\u4e00\u6b21\u91cd\u8981\u5c1d\u8bd5\u3002<\/p>\n

3. \u5929\u7136\u690d\u7269\u6210\u5206\u5c55\u73b0\u795e\u7ecf\u4fdd\u62a4\u6f5c\u529b<\/h3>\n

\u53d1\u8868\u5728\u300aBiochemical and Biophysical Research Communications\u300b\u4e0a\u7684\u7814\u7a76\uff0c\u901a\u8fc7\u7f51\u7edc\u836f\u7406\u5b66\u548c\u5b9e\u9a8c\u9a8c\u8bc1\uff0c\u63ed\u793a\u4e86\u4f97\u65cf\u4f20\u7edf\u836f\u7528\u690d\u7269”\u91ce\u6728\u74dc”\uff08Stauntonia brachyanthera\uff09\u5bf9\u6297\u963f\u5c14\u8328\u6d77\u9ed8\u75c7\u7684\u4f5c\u7528\u673a\u5236\u3002\u7814\u7a76\u9884\u6d4b\u4e86\u591a\u4e2a\u6d3b\u6027\u6210\u5206\u53ca\u5176\u4f5c\u7528\u9776\u70b9\uff0c\u4e3a\u4ece\u5929\u7136\u4ea7\u7269\u4e2d\u5f00\u53d1AD\u8f85\u52a9\u6cbb\u7597\u836f\u7269\u63d0\u4f9b\u4e86\u79d1\u5b66\u4f9d\u636e\u3002<\/p>\n

4. \u6b4c\u5531\u7597\u6cd5\uff1a\u7528\u97f3\u4e50\u70b9\u4eae\u8ba4\u77e5\u75c7\u60a3\u8005\u7684\u751f\u6d3b<\/h3>\n

\u300aJournal of Alzheimer’s Disease\u300b\u53d1\u8868\u4e86\u4e00\u9879\u6709\u8da3\u7684\u524d\u77bb\u6027\u4ea4\u53c9\u8bd5\u9a8c\uff1a\u6bd4\u8f83\u6b4c\u5531\u4e0e\u666e\u901a\u5bf9\u8bdd\u5bf9\u8ba4\u77e5\u75c7\u60a3\u8005\u5e78\u798f\u611f\u7684\u6539\u5584\u6548\u679c\u3002\u521d\u6b65\u7ed3\u679c\u663e\u793a\uff0c\u97f3\u4e50\u7c7b\u5e72\u9884\uff08\u5c24\u5176\u662f\u6b4c\u5531\uff09\u5728\u6539\u5584\u60c5\u7eea\u548c\u793e\u4ea4\u53c2\u4e0e\u5ea6\u65b9\u9762\u8868\u73b0\u51fa\u72ec\u7279\u4f18\u52bf\u3002\u97f3\u4e50\u89e6\u53d1\u7684\u4e0d\u4ec5\u662f\u8bb0\u5fc6\uff0c\u66f4\u662f\u60c5\u611f\u8fde\u63a5\u3002<\/p>\n

\u4e8c\u3001\u4e00\u4f4d\u5bb6\u5c5e\u7684\u5fc3\u58f0<\/h2>\n

\u770b\u5230\u8fd9\u4e9b\u7814\u7a76\u6210\u679c\uff0c\u6211\u7684\u5fc3\u60c5\u65e2\u6b23\u6170\u53c8\u6c89\u91cd\u3002<\/p>\n

\u6211\u7684\u6bcd\u4eb2\u57282017\u5e74\u88ab\u786e\u8bca\u4e3a\u963f\u5c14\u8328\u6d77\u9ed8\u75c7\u3002\u4ece\u6700\u521d\u7684\u5fd8\u5e26\u94a5\u5319\u3001\u53eb\u4e0d\u51fa\u719f\u4eba\u540d\u5b57\uff0c\u5230\u540e\u6765\u8ba4\u4e0d\u51fa\u56de\u5bb6\u7684\u8def\u3001\u5fd8\u8bb0\u5173\u7164\u6c14\u2026\u2026\u6211\u4eec\u773c\u7741\u7741\u770b\u7740\u5979\u4e00\u70b9\u4e00\u70b9\u5730”\u6d88\u5931”\u3002<\/p>\n

\u800c\u73b0\u5728\uff0c\u5979\u5df2\u7ecf\u5b8c\u5168\u4e0d\u8ba4\u8bc6\u6211\u4e86\u3002\u6709\u65f6\u5019\u6211\u53bb\u770b\u5979\uff0c\u5979\u4f1a\u793c\u8c8c\u5730\u5bf9\u6211\u70b9\u5934\u5fae\u7b11\uff0c\u50cf\u5bf9\u5f85\u4e00\u4e2a\u964c\u751f\u7684\u8bbf\u5ba2\u3002\u4f46\u6700\u8ba9\u6211\u5fc3\u788e\u7684\u662f\u2014\u2014\u5c3d\u7ba1\u5979\u5fd8\u4e86\u6211\u662f\u8c01\uff0c\u5374\u8fd8\u4f1a\u5076\u5c14\u63d0\u8d77\u6211\u7684\u540d\u5b57\u3002”\u5c0fX\u53bb\u54ea\u4e86\uff1f”\u5979\u4f1a\u8fd9\u6837\u95ee\u8eab\u8fb9\u7684\u4eba\u3002\u6211\u7684\u540d\u5b57\u8fd8\u7559\u5728\u5979\u7684\u8bb0\u5fc6\u788e\u7247\u91cc\uff0c\u4f46\u5979\u65e0\u6cd5\u628a\u90a3\u5f20\u8138\u548c\u6211\u8054\u7cfb\u8d77\u6765\u3002<\/p>\n

\u6bcf\u4e00\u6b21\u542c\u5230\u5979\u558a\u6211\u7684\u540d\u5b57\uff0c\u90fd\u662f\u4e00\u6b21\u6e29\u6696\u7684\u523a\u75db\u3002<\/p>\n

\u6240\u4ee5\uff0c\u5f53\u6211\u5728PubMed\u4e0a\u9010\u6761\u7ffb\u9605\u8fd9\u4e9b\u6700\u65b0\u6587\u732e\u65f6\uff0c\u6211\u6bd4\u4efb\u4f55\u4eba\u90fd\u6e34\u671b\u90a3\u4e9b\u7eb8\u9762\u4e0a\u7684”\u6709\u671b””\u53ef\u80fd””\u521d\u6b65\u9a8c\u8bc1”\u80fd\u5feb\u4e00\u70b9\u3001\u518d\u5feb\u4e00\u70b9\u8d70\u8fdb\u4e34\u5e8a\u3002\u6211\u6df1\u77e5\uff0c\u6bcf\u4e00\u4e2a\u79d1\u7814\u7a81\u7834\u80cc\u540e\uff0c\u90fd\u6709\u5343\u5343\u4e07\u4e07\u4e2a\u50cf\u6211\u4e00\u6837\u7684\u5bb6\u5c5e\u5728\u7b49\u5f85\u3002<\/p>\n

\u4e09\u3001\u6cbb\u7597\u524d\u666f\u5c55\u671b<\/h2>\n

\u4ece\u76ee\u524d\u7684\u8d8b\u52bf\u6765\u770b\uff0c2026\u5e74\u963f\u5c14\u8328\u6d77\u9ed8\u75c7\u7814\u7a76\u6b63\u5728\u8fdb\u5165\u4e00\u4e2a\u591a\u7ba1\u9f50\u4e0b\u7684\u65f6\u4ee3\uff1a<\/p>\n

    \n
  • \u751f\u7269\u6807\u5fd7\u7269\u5148\u884c\uff1a<\/strong>\u4eceA\u03b2\u3001tau\u5230\u795e\u7ecf\u9ed1\u8272\u7d20\uff0c\u8bca\u65ad\u7a97\u53e3\u4e0d\u65ad\u63d0\u524d<\/li>\n
  • \u836f\u7269\u5f00\u53d1\u591a\u6837\u5316\uff1a<\/strong>\u5c0f\u5206\u5b50\u6291\u5236\u5242\u3001\u5929\u7136\u4ea7\u7269\u3001\u514d\u75ab\u7597\u6cd5\u5e76\u884c\u63a8\u8fdb<\/li>\n
  • \u975e\u836f\u7269\u5e72\u9884\u53d7\u91cd\u89c6\uff1a<\/strong>\u97f3\u4e50\u3001\u8fd0\u52a8\u3001\u8ba4\u77e5\u8bad\u7ec3\u7b49\u7efc\u5408\u7ba1\u7406\u65b9\u6848\u65e5\u76ca\u5b8c\u5584<\/li>\n
  • \u8111\u80a0\u8f74\u5d2d\u9732\u5934\u89d2\uff1a<\/strong>\u77ed\u94fe\u8102\u80aa\u9178\u7b49\u80a0\u9053\u83cc\u7fa4\u4ee3\u8c22\u7269\u5728\u795e\u7ecf\u708e\u75c7\u4e2d\u7684\u8c03\u8282\u4f5c\u7528\u6210\u4e3a\u65b0\u70ed\u70b9<\/li>\n<\/ul>\n

    \u79d1\u5b66\u4ece\u6765\u4e0d\u4f1a\u4e00\u8e74\u800c\u5c31\uff0c\u4f46\u6bcf\u4e00\u6761\u65b0\u53d1\u73b0\u90fd\u5728\u7f29\u77ed\u6211\u4eec\u4e0e\u6cbb\u6108\u4e4b\u95f4\u7684\u8ddd\u79bb\u3002\u5e0c\u671b\u6709\u4e00\u5929\uff0c\u6211\u7684\u6bcd\u4eb2\u80fd\u5728\u67d0\u4e2a\u6e05\u9192\u7684\u77ac\u95f4\uff0c\u91cd\u65b0\u8ba4\u51fa\u7ad9\u5728\u5979\u9762\u524d\u7684\u662f\u8c01\u3002<\/p>\n

    \n

    \u6570\u636e\u6765\u6e90\uff1aPubMed \/ Acta Neuropathologica \/ Journal of Alzheimer’s Disease \/ Current Alzheimer Research \u7b49<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

    \u65e5\u671f\uff1a2026\u5e749\u670813\u65e5 \u4e00\u3001\u672c\u5468\u91cd\u78c5\u7814\u7a76\u4eae\u70b9 1. \u84dd\u6591\u6838\u5206\u5b50\u56fe\u8c31\u63ed\u793aAPOE\u4e0e\u963f\u5c14\u8328\u6d77\u9ed8\u75c7\u7684\u6df1\u5c42\u5173\u8054 \u53d1 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-817","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/word.hellsmart.top\/index.php\/wp-json\/wp\/v2\/posts\/817","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/word.hellsmart.top\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/word.hellsmart.top\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/word.hellsmart.top\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/word.hellsmart.top\/index.php\/wp-json\/wp\/v2\/comments?post=817"}],"version-history":[{"count":1,"href":"https:\/\/word.hellsmart.top\/index.php\/wp-json\/wp\/v2\/posts\/817\/revisions"}],"predecessor-version":[{"id":818,"href":"https:\/\/word.hellsmart.top\/index.php\/wp-json\/wp\/v2\/posts\/817\/revisions\/818"}],"wp:attachment":[{"href":"https:\/\/word.hellsmart.top\/index.php\/wp-json\/wp\/v2\/media?parent=817"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/word.hellsmart.top\/index.php\/wp-json\/wp\/v2\/categories?post=817"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/word.hellsmart.top\/index.php\/wp-json\/wp\/v2\/tags?post=817"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}